LL-37

A cathelicidin-derived antimicrobial peptide examined in laboratory immunological research.

LL-37 is a naturally occurring antimicrobial peptide produced by cleavage of the human cathelicidin precursor protein hCAP18. In the published literature it appears predominantly in innate-immunity and host-defense research models. Describing it as "studied in" these areas indicates where scientific attention has been directed, not a claim of any result. This page is background about the molecule as a research material and is not medical guidance or intended for human use.

Classification and structure

LL-37 is classified as a cathelicidin-derived host-defense peptide. It is a cationic, amphipathic peptide whose sequence begins with two leucine residues, giving the molecule its name. It has been the subject of research examining membrane interactions and innate-immune signaling, and it is handled in the laboratory as a defined peptide research compound.

Areas of research

LL-37 appears across several defined areas of the research literature.

• Innate immunity — Investigated in research examining host-defense peptides and innate-immune signaling.
• Membrane interaction — Appears in the literature on peptide-membrane biophysics and microbial membrane research.
• Immunomodulation research — Has been the subject of research examining immune-cell responses in vitro.

As always in this library, describing a compound as “studied in” an area is a statement about where scientific attention has gone — not a claim that it produces any result in humans or animals.

Handling and verification

Store lyophilized material cold and protected from light and moisture, following standard peptide-handling practice. Every in-stock lot ships with a verifiable third-party certificate of analysis (COA) documenting identity and purity.