IGF-1 LR3

Long R3 insulin-like growth factor-1 analog

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is classified as an analog of insulin-like growth factor-1. It is an 83-amino-acid protein bearing sequence modifications and appears in the literature on growth-factor signaling and cell-culture research. This page is background about the molecule as a research material and is not medical guidance and not intended for human or animal use.

Classification and structure

IGF-1 LR3 is a recombinant analog of human IGF-1 extended with a 13-residue N-terminal peptide and carrying an arginine substitution at position 3 (the "Long R3" designation), giving 83 amino acids. These modifications are described in the literature as reducing binding to IGF-binding proteins relative to native IGF-1. It is classified as a growth-factor research protein.

Areas of research

In the scientific literature this protein appears across the following research areas.

• Growth-factor signaling — Investigated in laboratory models of IGF-1 receptor signaling pathways.
• Cell-culture research — Appears as a supplement in in-vitro studies of cell proliferation and differentiation.
• Binding-protein studies — Featured in work on modified IGF-1 sequences and their interaction with IGF-binding proteins.

As always in this library, describing a compound as “studied in” an area is a statement about where scientific attention has gone — not a claim that it produces any result in humans or animals.

Handling and verification

Store lyophilized protein cold and protected from light per standard peptide/protein handling practice. Every in-stock lot ships with a verifiable third-party certificate of analysis (COA).