CJC-1295 No DAC

Growth-hormone-releasing hormone (GHRH) analog peptide

CJC-1295 No DAC, also called Mod GRF 1-29, is classified as a growth-hormone-releasing hormone (GHRH) analog peptide. It is a modified fragment based on the GHRH(1-29) sequence and appears in the preclinical literature on the somatotropic axis. This page is background about the molecule as a research material and is not medical guidance and not intended for human or animal use.

Classification and structure

CJC-1295 No DAC is a synthetic 29-amino-acid peptide derived from the N-terminal region of endogenous GHRH, incorporating substitutions intended to improve stability relative to native GHRH. Without the Drug Affinity Complex (DAC) modification, it is structurally distinct from the DAC-bearing variant. It is classified as a GHRH-receptor-directed analog for research purposes.

Areas of research

In the scientific literature this peptide appears across the following research areas.

• GHRH-receptor research — Investigated in laboratory models of GHRH-receptor binding and signaling within the somatotropic axis.
• Peptide analog design — Appears in studies comparing modified GHRH sequences for stability and receptor interaction.
• Analytical characterization — Used as a reference material in peptide purity, identity, and stability studies.

As always in this library, describing a compound as “studied in” an area is a statement about where scientific attention has gone — not a claim that it produces any result in humans or animals.

Handling and verification

Store lyophilized peptide cold and protected from light per standard peptide handling practice. Every in-stock lot ships with a verifiable third-party certificate of analysis (COA).